Relevant generalization starts here (and here = 2)

What Starts Here Changes the World.

All PBL Starts Here: The Problem

One essential piece of implementing of PBL is the problem. There have been calls from practitioners in the PBL field for a systematic process for designing effective PBL problems. Yet, the research efforts to explore, develop, and test PBL problem design methods or processes are still sparse. From an instructional designer and researcher’s perspective, I deem problem design to be the first step...

Tissue factor and thrombosis: The clot starts here.

Thrombosis, or complications from thrombosis, currently occupies the top three positions in the cardiovascular causes of morbidity and mortality in the developed world. There are a limited number of safe and effective drugs to prevent and treat thrombosis. Animal models of thrombosis are necessary to better understand the complex components and interactions involved in the formation of a clot. ...

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Motivated by recent developments in solid electrolytes based on lithium phosphorous oxynitride (LiPON) materials, we carried out computer simulations in order to develop an understanding of the detailed mechanisms of ionic transport. Starting with crystalline Li3PO4, we investigated some possible structures of isolated defects associated with extrinsic Li ion vacancies and interstitials. In par...

Here, there, and everywhere

T he main hurdle for genome sequencing projects these days is no longer the effort and cost of generating sequence data—which has become exponentially cheaper—but the capacity to analyse huge amounts of data and make sense of it. This endeavour is made harder by another problem that has begun to emerge over the past years: DNA contamination. Contamination impacts both sequence data generation, ...